Check this box if you wish to have a copy mailed to you. Taking effectiveness, safety, side effects, and cost into account, we have chosen the following as Consumer Reports Best Buy Drugs if you have any of these conditions: Aspirin — If you have peripheral vascular disease, or had a stroke or ministroke TIA Aspirin plus clopidogrel Plavix — If you've been diagnosed with acute coronary syndrome e. Aspirin plus extended-release dipyridamole Aggrenox —you've had a stroke or ministroke TIA.
Clopidogrel Plavix - If you can't take aspirin and have been diagnosed with acute coronary syndrome or had a stent implanted. Editor's Note: These materials are made possible by a grant from the state Attorney General Consumer and Prescriber Education Grant Program, which is funded by the multi-state settlement of consumer-fraud claims regarding the marketing of the prescription drug Neurontin gabapentin.
Choose from cars, safety, health, and more! Already signed-up? Manage your newsletters here too. See your savings. Mobile Get Ratings on the go and compare while you shop Learn more.
Make a Donation Newsletters Give a Gift. That means the implications of this research could affect around a million patients throughout the country who want to avoid bleeding and use the most advanced drugs. Current guidelines recommend treating this population with a triple therapy of a vitamin K antagonist like warfarin, known as Coumadin, along with dual antiplatelet therapy, such as aspirin and clopidogrel, but that regimen leads to major bleeding in some people.
Many patients are requesting newer drugs like rivaroxaban, or Xarelto, in place of warfarin, which is notoriously difficult to manage. Three medications, lower dose: Very low-dose rivaroxaban plus dual antiplatelet therapy such as aspirin and clopidogrel. Three medications, standard dose: Triple therapy with vitamin K antagonist, such as warfarin, plus dual antiplatelet therapy aspirin and clopidogrel.
Both of the rivaroxaban groups were designed to reduce the risk of bleeding, either through a very low dose of rivaroxaban or through limiting the number of total drugs being taken. We are reassured that there were no differences in the number of strokes or heart attacks in all three groups, but that was not the primary outcome the study was looking for, so more data are needed. For my patients who currently use rivaroxaban to prevent a stroke, we now have good data about how to safely treat them if they need a stent placed in their heart.
Barnes: There is still more to learn about how to safely care for patients who have a risk of stroke and a risk of heart attack. People were given either Plavix or aspirin for up to 3 years. Compared with those taking aspirin, fewer people taking Plavix had a stroke or heart attack.
But there was no difference between the two treatment groups for the percentage of people who died from cardiovascular events.
In addition to the uses listed above, Plavix may be used off-label. And you may wonder if Plavix is used for certain other conditions. CABG is a type of open-heart surgery that helps improve blood flow to your heart. During CABG surgery, an artery or vein is taken from one part of your body such as your leg.
This way, blood can flow into an area of heart muscle that would otherwise be blocked from blood flow. The combination of drugs may also help to keep the newly grafted vessel flexible. Stents are mesh tubes that are sometimes placed into your arteries to keep the arteries open. Stents are usually placed when someone has a blockage in their artery that is stopping blood from flowing through the artery. This drug helps to reduce the risk of a blood clot forming inside the stent.
However, Plavix is also sometimes prescribed for a while after a stent is placed. The length of Plavix treatment depends on if the stent placed is a drug-eluting stent a stent that gives off a drug or a bare metal stent.
Atrial fibrillation is a type of heart arrythmia abnormal rate or rhythm of your heart beat. People with atrial fibrillation have a higher risk of blood clots forming inside their heart. This is because their heart is not pumping their blood properly. Blood clots are dangerous because they can travel inside your body and may get trapped in smaller vessels. If this happens, the clots can cut off blood flow to your heart, lungs, or brain.
Sometimes, Plavix is prescribed to help prevent blood clots from forming in people who have both atrial fibrillation and acute coronary syndrome. Plavix for prevention or treatment of deep vein thrombosis not an appropriate use. Plavix is not approved to treat or prevent deep vein thrombosis DVT. Plavix is not approved to treat elevated cholesterol. Plavix is often prescribed in combination with other drugs. Note: Some of the drugs listed below are used off-label.
Plavix is often prescribed in combination with aspirin to treat various conditions. The combination of Plavix and aspirin is called dual antiplatelet therapy. This is because both drugs work to stop your platelets from sticking together and forming dangerous clots. Several studies have shown a benefit to using these drugs together rather than taking either of the drugs alone.
Plavix is FDA-approved for use in combination with aspirin to prevent heart attack and stroke in people with acute coronary syndrome ACS.
Plavix may be used in combination with an anticoagulant blood thinner in some people who have conditions such as atrial fibrillation, or in people who have very high risk of a cardiovascular event. Cardiovascular events include heart attack and stroke. The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
The typical dosage of Plavix for acute coronary syndrome ACS depends on whether you have:. The typical dosage of Plavix is one mg tablet taken by mouth once daily. It can be taken with or without food. Your doctor may recommend that you start Plavix therapy by taking a loading dose. With a loading dose, the drug is given to you at a dosage higher than the typical dosage. A loading dose is used to increase the level of the drug in your body right away.
The typical loading dosage of Plavix is mg four mg tablets or one mg tablet taken by mouth one time. After taking your loading dose of Plavix, your doctor will recommend the dosage of Plavix that you should continue to take each day. The typical dosage of Plavix for people with peripheral artery disease PAD , recent stroke , or recent heart attack is one mg tablet taken by mouth once daily. If you miss a dose of Plavix, try to take it as soon as you remember. Doing this may increase your risk of serious side effects.
A medication timer may be useful, too. You might. Plavix is meant to be used as a long-term treatment. Other drugs are available that can reduce your risk of cardiovascular events, such as heart attack and stroke.
Some may be better suited for you than others. They can tell you about other medications that may work well for you. The drugs listed below all help to prevent your body from making too many blood clots. However, these drugs each work in slightly different ways. Because of this, some drugs may work better for you than other drugs. Note: Some of the drugs listed above are used off-label. You may wonder how Plavix compares to other medications that are prescribed for similar uses. Here we look at how Plavix and Brilinta are alike and different.
Plavix contains the drug clopidogrel, while Brilinta contains the drug ticagrelor. These drugs belong to the same class of medications called platelet inhibitors. Plavix and Brilinta are both approved to prevent cardiovascular complications, such as heart attack and stroke , in people who have acute coronary syndrome ACS. This syndrome is caused by a lack of blood flow to your heart due to a blockage. Unstable angina a type of chest pain and heart attack are two types of ACS.
Both Plavix and Brilinta are often prescribed for use in combination with aspirin. Plavix comes as tablets that are taken by mouth once each day. Brilinta comes as tablets that are taken by mouth twice each day. There is also a loading dose for Brilinta. Plavix and Brilinta belong to a class of drugs called platelet inhibitors.
Therefore, both medications can cause very similar side effects. Below are examples of these side effects. These lists contain examples of more common side effects that can occur with Plavix, with Brilinta, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Plavix, with Brilinta, or with both drugs when taken individually. In one clinical study, people who had experienced an ACS event within the past 24 hours took aspirin and either Plavix or Brilinta.
Researchers followed the people for up to 1 year to see if they would have a cardiovascular event such as heart attack, stroke, or cardiovascular-related death. By the end of the study, compared with people taking Plavix and aspirin, fewer people taking Brilinta and aspirin had experienced a cardiovascular event. For details on this study, see the Plavix package insert. Plavix and Brilinta are both brand-name drugs. A generic form of Plavix, called clopidogrel, is available for use.
However, a generic form of Brilinta is not yet available. The generic is considered to be just as safe and effective as the original drug. According to estimates on GoodRx. Here we look at how Plavix and Effient are alike and different.
Plavix contains the drug clopidogrel, while Effient contains the drug prasugrel. Both drugs belong to the same class of medications called platelet inhibitors.
Plavix and Effient are both approved to prevent cardiovascular events, such as heart attack and stroke , in people who have acute coronary syndrome ACS.
With ACS, there is a lack of blood flow to your heart due to blockage. And for each of these uses, Effient should only be given to people who will be having or have had percutaneous coronary intervention PCI treatment. With PCI, a thin, flexible tube is used to open up blood vessels that are narrowed because of plaque buildup. Effient is also approved to prevent blood clots from forming on or inside stents mesh tubes in people with ACS.
Plavix is also approved to prevent heart attack and stroke in people with peripheral artery disease PAD. Both Plavix and Effient are often prescribed for use in combination with aspirin. Effient comes as tablets that are taken by mouth twice each day. Plavix and Effient both belong to a class of drugs called platelet inhibitors.
These lists contain examples of more common side effects that can occur with Plavix, with Effient, or with both drugs when taken individually. Examples of serious side effects that can occur with both drugs when taken individually include the following:.
The use of Plavix and Effient has been directly compared in studies. In one clinical study , certain people were given aspirin and either Plavix or Effient for up to 15 months.
Researchers found that compared with those taking Plavix and aspirin, fewer people taking Effient and aspirin had experienced a heart attack, stroke, or cardiovascular-related death. Plavix and Effient are both brand-name drugs, but there are generic forms available for each drug. The generic form of Plavix is called clopidogrel, while the generic form of Effient is called prasugrel.
Plavix can interact with several other medications. It can also interact with certain supplements as well as certain foods. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe. Below are lists of medications that can interact with Plavix.
These lists do not contain all the drugs that may interact with Plavix. Before taking Plavix, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
0コメント